Additional file 3: of Composition and dynamics of the respiratory tract microbiome in intubated patients

Closed-reference OTU table. Closed-reference OTU taxonomic assignments. Sequence data was analyzed using the Quantitative Insights Into Microbial Ecology (QIIME) bioinformatics pipeline, version 1.8.0. Sequence alignment was performed via PyNAST, closed-reference operational taxonomic unit (OTU) formation, and taxonomic assignment was based on the Greengenes (13.8) taxonomy. Closed-reference OTUs were used in all comparisons between intubated subjects and healthy controls. (ZIP 90.8 KB)

闭参考操作分类单元（operational taxonomic unit, OTU）表及闭参考OTU分类学注释数据集。本序列数据采用版本1.8.0的微生物生态学定量分析（Quantitative Insights Into Microbial Ecology, QIIME）生物信息学流程进行分析。序列比对通过PyNAST完成，以闭参考法构建操作分类单元，并基于Greengenes（13.8版）分类数据库进行分类学注释。所有插管受试者与健康对照的组间比较均采用闭参考OTU开展分析。（ZIP 90.8 KB）