Treatment of dementia: recommendations of the Scientific Department of Cognitive Neurology and Aging of the Brazilian Academy of Neurology

ABSTRACT There is currently no cure for neurodegenerative or vascular dementias, but some pharmacological and non-pharmacological interventions may contribute to alleviate symptoms, slow disease progression and improve quality of life. Current treatment approaches are based on etiology, symptom profile and stage of dementia. This manuscript presents recommendations on pharmacological and non-pharmacological treatments of dementia due to Alzheimer’s disease, vascular cognitive impairment, frontotemporal dementia, Parkinson’s disease dementia, and dementia with Lewy bodies.

摘要
目前神经退行性疾病及血管性痴呆尚无治愈方案，但部分药物与非药物干预手段可缓解症状、延缓疾病进展并改善患者生活质量。当前的治疗策略均基于痴呆的病因、症状谱及疾病分期制定。本文针对阿尔茨海默病（Alzheimer’s disease）、血管性认知障碍（vascular cognitive impairment）、额颞叶痴呆（frontotemporal dementia）、帕金森病痴呆（Parkinson’s disease dementia）及路易体痴呆（dementia with Lewy bodies）的相关病症，给出了药物与非药物治疗方面的推荐建议。