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Expression Profile of Genes in Trabecular Meshwork Cells Treated with Dexamethasone

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE124114
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Treatment with glucocorticoids is known to cause ocular hypertension in humans which can lead to steriod-induced glaucoma We used microarrays to determine changes in gene expression in two human trabecular meshwork (TM) cell isolates (TM-4 and TM-2) from the same donor that could explain the increase in ocular hypertension. RNA was extracted from confluent cultures of trabecular meshwork cells treated with and without dexamethasone (DEX) for 6 days and prepared for hybridization on Affymetrix microarrays
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2019-09-18
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