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Published Orthogonal Replication, Independent External Replication Frontier, and Canonical Stable Scaffold Convergence Boundary of a Native Fracture-State Family in a Computational Longevity Discovery Pipeline (Trinity Claims #87-#124, 2026-03-27)

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Zenodo2026-03-28 更新2026-05-26 收录
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This version fixes the next honest cross-database milestone from the Trinity computational longevity-discovery pipeline. Claims #87-#124 establish an exact operational plateau for native fracture-state admission, orthogonal replication of the target TOP3A/RMI2/CCDC69 family in published huMAP3 layers, strong-core switch decomposition, arm-polarized fracture geometry, exact same-core response algebra, a locked falsification simplex, a strict same-core protocol, an exhaustive assay scorecard, a first external replication frontier, and a final phase-87 canonical-stable-scaffold layer in which official Reactome and MINT converge on the human BLM:TOP3A:RMI1:RMI2 repair scaffold while the CCDC69 extension arm and PITRM1 fracture outsider remain outside canonical external curation. This package contains the milestone report, claim documents, raw external evidence snapshots from official Reactome and MINT endpoints, summary tables, source files, and publication materials for the second honest cross-database boundary test of the Trinity fracture-state model. This is a computational discovery and preregistration package and not a completed causal validation study.

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2026-03-28
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