Additional file 1 of Genome-wide enhancer RNA profiling adds molecular links between genetic variation and human cancers

Additional file 1: Table S1 List of eRNAs in 30 cancer types from TCGA. Table S2 Summary of characteristics of individuals in the replication stage. Table S3 Probes or primers sequence used in the study. Table S4 Summary of eRNAQTLs in 30 cancers. Table S5 Enrichment of eRNAQTLs in the histone modification peaks. Table S6 Enrichment of eRNAQTLs in the binding site of transcription factors. Table S7 Enrichment of eRNAQTLs in the binding site of RNA binding proteins. Table S8 Expression patterns of eRNAs in 30 cancers from TCGA. Table S9 Putative target genes of eRNAs in 30 cancers from TCGA. Table S10 Correlations between eRNAs and immune infiltration in 30 cancers from TCGA. Table S11 Correlations between eRNAs and drug response in 30 cancers from TCGA. Table S12 Correlations between eRNAs and patients’ survival in 30 cancers from TCGA. Table S13 Enhancers identified in our colorectal cancer tissues. Table S14 Enhancers identified in our adjacent normal tissues. Table S15 Enhancer RNAs identified in our colorectal cancer tissues. Table S16 Enhancer RNAs identified in our adjacent normal tissues. Table S17 eRNAQTLs identified in our colorectal cancer tissues. Table S18 eRNAQTLs identified in our adjacent normal tissues. Table S19 Tissue specificity of eRNAQTLs identified in our tissues.

附加文件1：
表S1 来自癌症基因组图谱（The Cancer Genome Atlas, TCGA）的30种癌症的增强子RNA（enhancer RNA, eRNA）列表
表S2 验证阶段研究对象的特征汇总
表S3 本研究使用的探针或引物序列
表S4 30种癌症的增强子RNA数量性状位点（enhancer RNA quantitative trait locus, eRNAQTL）汇总
表S5 eRNAQTL在组蛋白修饰峰中的富集分析
表S6 eRNAQTL在转录因子结合位点中的富集分析
表S7 eRNAQTL在RNA结合蛋白结合位点中的富集分析
表S8 来自TCGA的30种癌症的eRNA表达模式
表S9 来自TCGA的30种癌症的eRNA潜在靶基因
表S10 来自TCGA的30种癌症的eRNA与免疫浸润的相关性分析
表S11 来自TCGA的30种癌症的eRNA与药物响应的相关性分析
表S12 来自TCGA的30种癌症的eRNA与患者生存的相关性分析
表S13 本研究结直肠癌组织中鉴定的增强子区域
表S14 本研究癌旁正常组织中鉴定的增强子区域
表S15 本研究结直肠癌组织中鉴定的eRNA
表S16 本研究癌旁正常组织中鉴定的eRNA
表S17 本研究结直肠癌组织中鉴定的eRNAQTL
表S18 本研究癌旁正常组织中鉴定的eRNAQTL
表S19 本研究组织中鉴定的eRNAQTL的组织特异性