Detection of the indicated APMV strains from the lower respiratory tract of rhesus macaques.*
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*This is a continuation of the experiment described in Table? 2. BAL was performed on days 2, 4, 6, and 8.†The 50 percent egg infectious dose (EID50) virus titer (expressed as log10 EID50 per mL) was determined as described in materials and methods. Limit of detection was 0.8 log10 per mL.‡The sum of daily titers (area under the curve) was used to determine magnitude of virus shedding. A value of 0.4 was used for samples with no detectable virus.§For calculation of daily means, a value of 0.4 log10 per mL was used for samples with no detectable virus.¶Shedding of wt APMV-5 was determined by limiting dilution assay of BAL fluid on Vero cells, followed by virus detection using a neuraminidase assay.
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2015-12-02



