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Crystal Structure of JAK1 in complex with compound 25

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Protein Data Bank Japan2024-10-16 更新2026-03-21 收录
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Crystal Structure of JAK1 in complex with compound 25 Descriptor: N-{cis-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclobutyl}propane-1-sulfonamide, Tyrosine-protein kinase JAK1 Authors: Han, S. Deposit date: 2017-10-19 Release date: 2018-01-17 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.08 Å) Cite: Identification of N-{cis-3-[Methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclobutyl}propane-1-sulfonamide (PF-04965842): A Selective JAK1 Clinical Candidate for the Treatment of Autoimmune Diseases. J. Med. Chem., 61, 2018

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2017-10-19
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