Distribution of dopamine 1 receptor positive neurons in the adolescent female mouse brain

High-resolution bright-field microscopy images of coronal brain sections showing dopamine 1 receptor positive neurons across the adolescent (35 days old) mouse brain. The dataset consists of eight image series covering the rostral part of the brain from Drd1a-EGFP mice. For each brain, every fourth section was processed by diaminobenzidine (DAB) immunohistochemistry using a polyclonal anti-GFP (RRID:AB_300798) antibody. The publication related to the dataset furthermore includes stereological counts of positive neurons in the prelimbic, infralimbic and insula cortex, as well as in dorsal and ventral striatum.

本数据集包含35日龄青春期小鼠全脑冠状脑片的高分辨率明场显微图像，可展示小鼠全脑内多巴胺1受体阳性神经元的分布情况。该数据集包含8组图像序列，均来自Drd1a-EGFP转基因小鼠的脑吻侧区域。针对每只小鼠的脑组织，每间隔3张脑片选取1张，使用多克隆抗GFP抗体（RRID:AB_300798）进行二氨基联苯胺（diaminobenzidine, DAB）免疫组化染色处理。与本数据集相关的发表文献还包含了前额叶边缘前区、边缘下皮层、岛叶皮层以及背侧纹状体和腹侧纹状体中阳性神经元的体视学计数数据。