SHV-1 class A beta-lactamase complexed with penem WAY185229
收藏Protein Data Bank Japan2024-10-30 更新2026-03-21 收录
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SHV-1 class A beta-lactamase complexed with penem WAY185229 Descriptor: (6,7-DIHYDRO-5H-CYCLOPENTA[D]IMIDAZO[2,1-B]THIAZOL-2-YL]-4,7-DIHYDRO[1,4]THIAZEPINE-3,6-DICARBOXYLIC ACID, CYCLOHEXYL-HEXYL-BETA-D-MALTOSIDE, beta-lactamase SHV-1 Authors: Nukaga, M, Venkatesan, A.M, Mansour, T.S, Hujer, A, Bonomo, R.A, Knox, J.R. Deposit date: 2003-07-25 Release date: 2004-09-14 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (2 Å) Cite: Structure-activity relationship of 6-methylidene penems bearing tricyclic heterocycles as broad-spectrum beta-lactamase inhibitors: crystallographic structures show unexpected binding of 1,4-thiazepine intermediates J.Med.Chem., 47, 2004
创建时间：
2003-07-25
