Transcriptomic analysis of the effect of Kap120 deletion

The effect of Kap120 deletion at transcriptional level was investigated by GRO analysis of the transcription rates (TR) and mRNA levels (RA) genome-wide. mRNA stabilities can be calculated as RA /TR for each gene in all samples.本研究通过全基因组范围内的转录速率（Transcription Rates, TR）与mRNA水平（mRNA Levels, RA）的GRO分析，探究了Kap120基因缺失在转录水平上所产生的效应。所有样本中每个基因的mRNA稳定性均可通过RA与TR的比值（RA/TR）计算得到。