ld50_zhu

## Dataset Details ### Dataset Description Acute toxicity LD50 measures the most conservative dose that can lead to lethal adverse effects. The higher the dose, the more lethal of a drug. - **Curated by:** - **License:** CC BY 4.0 ### Dataset Sources - [corresponding publication](https://doi.org/10.1021/tx900189p) ## Citation **BibTeX:** ```bibtex @article{Zhu2009, doi = {10.1021/tx900189p}, url = {https://doi.org/10.1021/tx900189p}, year = {2009}, month = oct, publisher = {American Chemical Society ({ACS})}, volume = {22}, number = {12}, pages = {1913--1921}, author = {Hao Zhu and Todd M. Martin and Lin Ye and Alexander Sedykh and Douglas M. Young and Alexander Tropsha}, title = {Quantitative Structure-Activity Relationship Modeling of Rat Acute Toxicity by Oral Exposure}, journal = {Chemical Research in Toxicology}} ```## 数据集详情 ### 数据集描述 急性毒性半数致死量（LD50）指可引发致命不良反应的最低保守给药剂量，药物剂量越高，其致死毒性越强。 - **整理方：** - **许可协议：** CC BY 4.0（知识共享署名4.0） ### 数据集来源 - [对应研究论文](https://doi.org/10.1021/tx900189p) ## 引用信息 **BibTeX 格式引用：** bibtex @article{Zhu2009, doi = {10.1021/tx900189p}, url = {https://doi.org/10.1021/tx900189p}, year = {2009}, month = oct, publisher = {美国化学会（ACS）}, volume = {22}, number = {12}, pages = {1913--1921}, author = {Hao Zhu and Todd M. Martin and Lin Ye and Alexander Sedykh and Douglas M. Young and Alexander Tropsha}, title = {经口暴露的大鼠急性毒性定量构效关系建模}, journal = {Chemical Research in Toxicology} }

搜集汇总

背景与挑战

背景概述

该数据集专注于急性毒性LD50测量，用于评估药物剂量与致死效应的关系，剂量越高毒性越强。数据基于2009年发表的定量结构-活性关系研究，遵循CC BY 4.0许可协议。