Development of gene expression signatures for knock down expression of ARL4C. Development of gene expression signatures for knock down expression of ARL4C

o further development of our gene expression approach to biodosimetry, we have employed whole genome microarray expression profiling as a discovery platform to identify genes with the potential to distinguish expression of ARL4C. Human primay GBM cell was transfected with control or eGFP-Sh-ARL4C lentivirus, 588 gene are down-regulated and 366 gene are down-regulated. Overall design: knock down expression of ARL4C induced gene expression in human GBM cell was measured. Three independent experiments were performed for each experiment