co-crystal structure of Lck and aminopyrimidine reverse amide 23
收藏Protein Data Bank Japan2023-08-30 更新2026-03-21 收录
下载链接：
https://pdbj.org/mine/summary/3byu
下载链接
链接失效反馈官方服务：
资源简介：
co-crystal structure of Lck and aminopyrimidine reverse amide 23 Descriptor: 2-methyl-N-{4-methyl-3-[(2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-5-yl)carbamoyl]phenyl}-3-(trifluoromethyl)benzamide, Proto-oncogene tyrosine-protein kinase LCK Authors: Huang, X. Deposit date: 2008-01-16 Release date: 2008-09-16 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structure-guided design of aminopyrimidine amides as potent, selective inhibitors of lymphocyte specific kinase: synthesis, structure-activity relationships, and inhibition of in vivo T cell activation. J.Med.Chem., 51, 2008
创建时间：
2008-01-16
