Deep sequencing datasets are used for gRNA library analysis for large-scale screens. Using a lentiviral library that targets sequences across back-splicing sites of highly expressed human circRNAs, we
The acetyltransferase KAT5/Tip60 is an epigenetic regulator of transcription and the DNA damage response. In Drosophila, Tip60 acetylates histones as part of the Dom-A complex, but it is unclear wheth
Etv2, an Ets-transcription factor, governs the specification of the earliest hemato-endothelial progenitors during embryogenesis. While the transcriptional networks duringhemato-endothelial developmen
This network was assembled automatically by INDRA (http://indra.bio) by processing all available biomedical literature with multiple machine reading systems, and integrating curated pathway databases.
