The gene expression profiles of antigen-primed wildtype and Ddit3-/- CD8 Pmel T cells
收藏NIAID Data Ecosystem2026-05-01 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE112823
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资源简介：
T cell undergoes ER stress during regular priming which may lead to T cell dysfunction in cancer. ER stress downstream sensor Chop (encoded by Ddit3 gene) negatively regulates CD8 T cell function and cytotoxicity. Because Chop is a C/EBP homologous transcription factor, we sorted antigen-primed wildtype or ddit3-/- Pmel CD8 T cells perform RNA-seq and gene expression profile analysis. CD8 T cells from wildtype or Ddit3-/- Pmel mice were stimulated by specific antigen gp10025-33 and the gene expression profiles were tested by RNA-seq
创建时间：
2024-03-08
