Serial co-immunoprecipitation to expand the protein interactome of the outer mitosomal membrane in Giardia lamblia

Giardia lamblia's outer mitosomal membrane protein repertoire was investigated using a series of co-immunoprecipitations which led to the discovery of novel associated components. This was assembled into a Giardia mitosomal protein interactome which expands beyond the organelle, reaching out to other subcellular compartments.