C. elegans ADARs promote organismal survival to pathogen infection

Here, we reveal that the Caenorhabditis elegans ADAR proteins promote survival of animals exposed to several opportunistic human pathogens. Our data indicate that ADARs help maintain proper levels of cuticular collagen genes, which in turn affects defense of the nematode to these bacteria. High throughput sequencing of L4 whole animals RNA-seq libraries exposed to either Pseudomonas aeruginosa strain PA14 or OP50