The ubiquitin ligase TRIM37 controls cancer-specific vulnerability to PLK4 inhibition
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https://www.ncbi.nlm.nih.gov/sra/SRP255637
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资源简介：
We show synthetic lethality between PLK4 inhibition-mediated centrosome loss and the overexpression of the ubiquitin ligase TRIM37 in cancer cells with amplification of Chr17q Overall design: Compare the effect of differential TRIM37 expression on global gene expression in untransformed hTERT RPE1 and neuroblastoma CHP-134 cells.
创建时间：
2020-09-21
