Additional file 13: of Bromodomain protein 4 discriminates tissue-specific super-enhancers containing disease-specific susceptibility loci in prostate and breast cancer
We sorted GFP-labeled 4T1 cells from primary tumors and lung metastases and performed methylation-seq. Compare DNA methylation levels between primary tumors and lung metastases in 4T1 mouse mammary tu
The ability to induce pluripotent stem cells from committed, somatic human cells provides tremendous potential for regenerative medicine. However, there is a defined neoplastic potential inherent to s
Epigenetic mechanisms such as DNA methylation or histone modifications are essential for the regulation of gene expression and development of tissues. Alteration of epigenetic modifications can be use
