Crystal Structure of HIV-1 protease mutants R8Q complexed with inhibitor GRL-0519
收藏Protein Data Bank Japan2023-09-20 更新2026-03-21 收录
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Crystal Structure of HIV-1 protease mutants R8Q complexed with inhibitor GRL-0519 Descriptor: (3R,3aS,3bR,6aS,7aS)-octahydrodifuro[2,3-b:3',2'-d]furan-3-yl [(1S,2R)-1-benzyl-2-hydroxy-3-{[(4-methoxyphenyl)sulfonyl](2-methylpropyl)amino}propyl]carbamate, HIV-1 protease Authors: Zhang, H, Wang, Y.-F, Weber, I.T. Deposit date: 2012-10-03 Release date: 2013-08-21 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.46 Å) Cite: Novel P2 tris-tetrahydrofuran group in antiviral compound 1 (GRL-0519) fills the S2 binding pocket of selected mutants of HIV-1 protease. J.Med.Chem., 56, 2013
创建时间：
2012-10-03
