Description of cases and controls and their genotypes at MTHFR polymorphism rs1801133.

Abbreviations: NR, not reported; T2DM, type 2 diabetes mellitus; PCR-RFLP, polymerase chain reaction assay based on restriction fragment length polymorphism.aDefined as serious complications aside from the more frequent clinical manifestations of T2DM such as hyperlipidaemia, hypertension and obesity.bReported as either “median (range)” or as “mean ± standard deviation”, unless indicated otherwise.cP value for Hardy-Weinberg equilibrium for rs1801133 genotype among controls.