Custom Microbial Reference Database and Predicted peptides across 11cancer types (part 1) for "Microbial transcriptional reprogramming defines tumour-restricted antigens from taxonomically overlapping microbiomes"

This repository supports the study titled "Microbial transcriptional reprogramming defines tumour-restricted antigens from taxonomically overlapping microbiomes" by providing: Antigen Analysis Results: Microbial antigen predictions across 11 cancer types (including in-house CRC and pan-cancer datasets). The file Pan-CancerMicrobialAntigensAnalysis-MHCII_part2.zip is available at [Zenodo link: 10.5281/zenodo.15043056]. Custom Microbial Reference Datasets: A curated database of 4,342 species (545 genera, ~10M proteins), filtered for human-tumor relevance using LLM-based annotation and manual curation. Includes microbial genomes and protein reference sequences.