Synthetic Route to Chiral Indolines via Ring-Opening/C–N Cyclization of Activated 2‑Haloarylaziridines
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https://figshare.com/articles/dataset/Synthetic_Route_to_Chiral_Indolines_via_Ring_Opening_C_N_Cyclization_of_Activated_2_Haloarylaziridines/2422441
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资源简介：
A practical approach for the synthesis
of 3-substituted indolines
via regio- and stereoselective SN2-type ring-opening of
2-(2-halophenyl)-N-tosylaziridines with heteroatomic
nucleophiles (O, N, and S) followed by palladium-catalyzed intramolecular
C–N cyclization is reported in excellent yields (up to >99%)
and enantiomeric excess (ee 99%).
创建时间：
2016-02-19
