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Crystal structure of BRD2(BD2) mutant with ligand ET bound (METHYL (2R)- 2-[(4S)-6-(4-CHLOROPHENYL)-8-METHOXY-1-METHYL-4H-[1,2,4]TRIAZOLO[4,3-A][1, 4]BENZODIAZEPIN-4-YL]BUTANOATE)

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Protein Data Bank Japan2023-09-20 更新2026-03-21 收录
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https://pdbj.org/mine/summary/4qew
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Crystal structure of BRD2(BD2) mutant with ligand ET bound (METHYL (2R)- 2-[(4S)-6-(4-CHLOROPHENYL)-8-METHOXY-1-METHYL-4H-[1,2,4]TRIAZOLO[4,3-A][1, 4]BENZODIAZEPIN-4-YL]BUTANOATE) Descriptor: Bromodomain-containing protein 2, GLYCEROL, NICKEL (II) ION, ... Authors: Tallant, C, Baud, M, Lin-Shiao, E, Chirgadze, D.Y, Ciulli, A. Deposit date: 2014-05-19 Release date: 2014-10-29 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Chemical biology. A bump-and-hole approach to engineer controlled selectivity of BET bromodomain chemical probes. Science, 346, 2014
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2014-05-19
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