Elk1 Directs a Critical Component of Growth Signaling by the Androgen Receptor in Prostate Cancer

ChEBI2013-05-02 更新2026-07-21 收录

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-34589 数据链接链接失效反馈

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Elk1 Directs a Critical Component of Growth Signaling by the Androgen Receptor in Prostate Cancer

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2013-05-02

From HER2/Neu signal cascade to androgen receptor and its coactivators: A novel pathway by induction of androgen target genes through MAP kinase in prostate cancer cells

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Overexpression of the HER2/Neu protooncogene has been linked to the progression of breast cancer. Here we demonstrate that the growth of prostate cancer LNCaP cells can also be increased by the stable

PubMed Central1999-05-11 更新60

5′-Substituted Amiloride Derivatives as Allosteric Modulators Binding in the Sodium Ion Pocket of the Adenosine A 2A Receptor

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分子药理学

The sodium ion site is an allosteric site conserved among many G protein-coupled receptors (GPCRs). Amiloride 1 and 5-(N,N-hexamethylene)amiloride 2 (HMA) supposedly bind in this sodium ion site and

NIAID Data Ecosystem40

The miR-96 and RARG signaling axis governs androgen signaling and prostate cancer progression VI

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Expression levels of retinoic acid receptor gamma (NR1B3/RARG, encodes RARG), are commonly reduced in prostate cancer (PCa). Therefore we sought to establish the cellular and gene regulatory consequen

NIAID Data Ecosystem30

Data_Sheet_1_Inhibitory Receptor Crosslinking Quantitatively Dampens Calcium Flux Induced by Activating Receptor Triggering in NK Cells.PDF

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Natural killer (NK) cell function is regulated by a balance between activating and inhibitory receptors, but the details of this receptor interplay are not extensively understood. We developed a flow

NIAID Data Ecosystem60

Figure S1 - Functional Domains of Androgen Receptor Coactivator p44/Mep50/WDR77and Its Interaction with Smad1

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The interaction among AR, p44, Smad1 was detected by Co-immunoprecipitation in C4-2B cells. AR-p44-Smad1 is in an endogenous complex. (PPT)

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