Invasive breast carcinoma of no special type - Female, 37 - Tissue image [6250730010627281]

This is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 37Clinical description: Palpable tumor of right breast, diameter 4 cm. 24 x 20 mm hypoechoic tumor on ultrasound. Core needle biopsy: invasive breast carcinoma.Gender: FemaleDiagnosis:Classification: ICD-O_3.2Classification code: DUCTAL AND LOBULAR NEOPLASMSDiagnosis: Invasive breast carcinoma of no special typeResult of the histopathological examination: Invasive breast carcinoma (NOS) NHG 3 (3+3+3: 21 mitoses/10 HPF): ER-, PR-, HER2 1+, Ki-67 90%.Sample:Material: FFPECollecting method: Surgical specimenTopography: BREASTOrgan: BREASTTissue: Upper-inner quadrant of breastType of staining: positive/IHCStaining: Not applicableAntibody: ERTechnology:Equipment: Pannoramic 250 3DHistechLens: 20xOrganization:Source: Medical University Gdańsk

本数据集为格但斯克医科大学（Medical University Gdańsk）采集并存入ZMDL-GUMED数据库的乳腺组织样本组织病理图像。该样本图像采用Pannoramic 250 3DHistech玻片扫描仪（20倍放大倍率）拍摄，并以DICOM格式存储。

患者与临床详情如下：年龄37岁，女性；临床特征为右侧乳腺可触及直径4cm的肿物，超声检查显示存在24×20mm的低回声肿物；空心针穿刺活检结果提示浸润性乳腺癌。

诊断相关信息：分类标准采用国际疾病分类肿瘤学版第3.2版（ICD-O_3.2），分类编码为导管与小叶肿瘤（DUCTAL AND LOBULAR NEOPLASMS）；最终确诊诊断为非特殊类型浸润性乳腺癌。

组织病理检查结果：非特殊类型浸润性乳腺癌，诺丁汉组织学分级（NHG）3级（核分裂象计数为每10个高倍视野（High Power Field, HPF）21个，即3+3+3评分）；雌激素受体（ER）阴性、孕激素受体（PR）阴性、人表皮生长因子受体2（HER2）1+，Ki-67增殖指数为90%。

样本详情如下：样本材质为福尔马林固定石蜡包埋（Formalin-Fixed Paraffin-Embedded, FFPE）组织，采集方式为手术标本；部位为乳腺（BREAST），器官为乳腺（BREAST），组织定位为乳腺内上象限；染色类型为免疫组化（IHC）阳性结果，染色方案无特殊适配要求；检测抗体为ER；技术设备为Pannoramic 250 3DHistech玻片扫描仪，物镜倍率为20×；数据来源机构为格但斯克医科大学（Medical University Gdańsk）。