A three-dimensional thalamocortical dataset for characterizing brain heterogeneity: Region of Interest Annotations (Nrrd)

In this dataset, we provide a collection of images acquired from multiple brain regions that span an intact thalamocortical pathway (Agmon & Connors, 1991). The data was acquired using synchrotron X-ray microCT at 1.17 micron isotropic resolution. Along with these images, we provide annotations of regions of interest for the same images. All of the images are stored as tiffs and the annotations are stored as Nrrd files which can be easily opened in Fiji or Python and converted to other formats. The annotated images are located 58.5 microns apart (virtual section) from one another. The labels are 0-> no label; 1-> cortex; 2-> striatum; 3-> trn; 4-> vp; 5-> zona incerta; 6-> internal capsule; 7-> hypothalamus; 8-> corpus callosum.

本数据集收录了采自多个脑区的成像数据，覆盖完整的丘脑皮层通路（thalamocortical pathway；相关研究参见Agmon与Connors，1991）。本数据集的数据采用同步辐射X射线显微CT（synchrotron X-ray microCT）采集，各向同性分辨率达1.17微米。随上述图像同步提供的，还包含对应图像的感兴趣区域标注结果。所有图像均以TIFF格式存储，标注结果则存储为Nrrd格式文件，可直接在Fiji或Python中打开，并可便捷转换为其他格式。带标注的图像以虚拟切片形式呈现，相邻图像间的间距为58.5微米。标注标签的定义如下：0→无标注；1→大脑皮层（cortex）；2→纹状体（striatum）；3→丘脑网状核（thalamic reticular nucleus，TRN）；4→腹侧丘脑核（ventral posterior nucleus，VP）；5→未定带（zona incerta）；6→内囊（internal capsule）；7→下丘脑（hypothalamus）；8→胼胝体（corpus callosum）。