All About the Base – e-Isomerization of Terminal Propargyl Compounds towards Synthesis of Allenes and Phenols

Herein, we present a mild, efficient and selective electrochemical method for terminal allenes synthesis through isomerization of propargyl compounds. We postulate that the process occurs through in-situ electrochemically generation of a strong base. The proposed mechanism is supported by calculations - the reaction thermodynamics together with other computed parameters, combined with kinetic model sensitivity analysis, clarifies the role of the applied current in controlling the reaction pathway. Electrochemical pathway allows for not only selective synthesis of allenes but also phenols.