five

WP3658 - Wnt/beta-catenin signaling in leukemia - Homo sapiens

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ndexbio.org/viewer/networks/2eff4fe3-5c6c-11ec-b3be-0ac135e8bacf
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The Wnt/Beta-catenin pathway mediates the transcription of proteins important for maintenance and growth of hematopoietic stem cells. The inhibition of Wnt leads to protein degradation through Beta-Catenin activation by the Axin/APC/CK1/GSK3B protein complex. This pathway is based on figure 5 from Misaghian et al. Proteins on this pathway have targeted assays available via the [CPTAC Assay Portal](https://assays.cancer.gov/available_assays?wp_id=WP3658).
创建时间:
2025-04-17
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