While oncogenes can potentially be inhibited with small molecules, the loss of tumor suppressors is more common and presents a conundrum for precision therapy because the proteins are no longer presen
Triplet repeat siRNAs as found amplified in diseases such as Huntingtons disease can be used to kill cancer cells RNA isolated from HeyA8 cells 48 hrs after transfection with either a nontargeting siR
Genes nearest the sites are shown below the tumor names. Predicted or known protein function and the distance and orientation of the insertions with respect to the nearby gene are shown. All these ins