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Ikoamide, an Antimalarial Lipopeptide from an Okeania sp. Marine Cyanobacterium

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Figshare2020-02-10 更新2026-04-28 收录
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https://figshare.com/articles/dataset/Ikoamide_an_Antimalarial_Lipopeptide_from_an_i_Okeania_i_sp_Marine_Cyanobacterium/11831235
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An antimalarial lipopeptide, ikoamide, was isolated from an Okeania sp. marine cyanobacterium. Its gross structure was established by spectroscopic analyses, and the absolute configuration was clarified based on a combination of chiral-phase HPLC analyses, spectroscopic analyses, and derivatization reactions. Ikoamide showed strong antimalarial activity with an IC50 value of 0.14 μM without cytotoxicity against human cancer cell lines at 10 μM.
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2020-02-10
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