De novo histoid leprosy in a Colombian patient with multiple skin nodules on the ears and extremities

Abstract Histoid leprosy is an uncommon form of lepromatous leprosy with distinct clinical, histopathological, immunological, and bacteriological features. This variant usually occurs in multibacillary patients who have irregular or inadequate treatment. Herein, we report a case of de novo histoid leprosy diagnosed in a patient from Cali, Colombia. In endemic areas, histoid leprosy should be in the differential diagnosis of any patient presenting with skin nodules. Early diagnosis and appropriate treatment are recommended for mitigating the impact of histoid leprosy cases, which are important reservoirs of Mycobacterium leprae.

摘要：组织样麻风（Histoid leprosy）是一种罕见的瘤型麻风（lepromatous leprosy）亚型，具备独特的临床、组织病理、免疫与细菌学特征。该亚型多发生于接受不规则或不规范治疗的多菌型患者。本文报告1例来自哥伦比亚卡利市的新发组织样麻风病例。在麻风流行地区，对于出现皮肤结节的患者，组织样麻风应纳入鉴别诊断范畴。鉴于组织样麻风病例是麻风分枝杆菌（Mycobacterium leprae）的重要储存宿主，早期诊断与规范治疗对于减轻其疾病危害具有重要意义。