Additional file 1 of Comparative gene expression profiling between optic nerve and spinal cord injury in Xenopus laevis reveals a core set of genes inherent in successful regeneration of vertebrate central nervous system axons

Additional file 1. Cuffdiff2 differential expression data. Tabs are for each injury condition and time point vs. their relevant controls (N = 3 biological replicates, each). Tabs PW1–3) Tadpole spinal cord injury (SCI) hindbrain vs. age-matched, unoperated control hindbrain at 3 days, 1 week, and 3 weeks, respectively; PW4–6) Juvenile frog SCI hindbrain at 3 days, 1 week, and 3 weeks vs. unoperated control hindbrain; PW7–9) juvenile frog optic nerve crush (ONC) eye vs. the contralateral unoperated eye at 3 days, 11 days, and 3 weeks, respectively. Abbreviations: chr, chromosome; cntrl, control; FPKM, fragments per kilobase of transcript per million mapped reads; ONC, optic nerve crush; p, the calculated probability for a single given gene that the observed difference represented no change in expression (i.e., log2(fold change) = 0); q, false discovery rate-adjusted (FDR) p-value [14]; significant, “yes” if q

附加文件1：Cuffdiff2差异表达数据。各工作表对应一种损伤条件与时间点与其相应对照组的比较（每组均设置3次生物学重复）。其中工作表PW1~3分别对应3天、1周、3周时，蝌蚪脊髓损伤（spinal cord injury, SCI）后脑与同龄未手术对照后脑的比较；工作表PW4~6分别对应3天、1周、3周时，幼蛙脊髓损伤后脑与未手术对照后脑的比较；工作表PW7~9分别对应3天、11天、3周时，幼蛙视神经钳夹术（optic nerve crush, ONC）组眼球与对侧未手术对照眼球的比较。缩写说明：染色体（chromosome, chr）；对照（control, cntrl）；每百万比对读段中每千碱基转录本的片段数（fragments per kilobase of transcript per million mapped reads, FPKM）；p值为针对单个给定基因计算得到的概率，表示观测到的表达差异实为无表达变化（即log₂(折叠变化)=0）；q值为经错误发现率（false discovery rate, FDR）校正后的p值[14]；显著差异标记为若q值满足条件时标记为"yes"。