Crystal structure of EGFR 696-1022 T790M/C797S in complex with LS_2_40
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Crystal structure of EGFR 696-1022 T790M/C797S in complex with LS_2_40 Descriptor: 5-chloranyl-N2-[3-chloranyl-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]-N4-(2-dimethylphosphorylphenyl)pyrimidine-2,4-diamine, Epidermal growth factor receptor Authors: Zhu, S.J, Yun, C.H. Deposit date: 2021-05-05 Release date: 2022-04-20 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.662 Å) Cite: Optimization of Brigatinib as New Wild-Type Sparing Inhibitors of EGFR T790M/C797S Mutants. Acs Med.Chem.Lett., 13, 2022
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2021-05-05
