Worldwide metropolitan cases, with and without 95% travel restrictions implemented sequentially after the first 1,000 cases have been identified in each city, for an epidemic with R0 = 1.7.

1The end of the epidemic is determined when there are no further cases worldwide.2These data represent means and standard deviations for all 100 runs, including the runs in which the disease did not develop a pandemic state and did not reach the U.S.Note: The data are presented for only the 155 major cities, not the entire world population.