Supplementary Table 5 from Network Analysis Reveals Synergistic Genetic Dependencies for Rational Combination Therapy in Philadelphia Chromosome–Like Acute Lymphoblastic Leukemia

The gene regulatory network used in this study. The network consists of 5,959 genes and 108,281 regulatory interactions as we previously detailed (13). Interactions were collected from three public pathway databases that were manually curated by experts: Reactome (19) (1597 pathways), KEGG (18) (195 pathways) and NCI-Nature Pathway Interaction database (20) (745 pathways).