CCDB_4070.jpg

Triple labeled confocal image of the dentate gyrus of a transgenic mouse engineered to overexpress alpha synuclein under the Thy-1 promotor, immunolabeled for mGluR5 (red), alpha synuclein (green) and counterstained with DAPI (blue) to reveal cell nuclei.

本数据集为三重标记共聚焦显微镜图像，样本为经基因工程改造、可在Thy-1启动子（Thy-1 promoter）调控下过表达α-突触核蛋白（alpha synuclein）的转基因小鼠的齿状回组织。该样本以代谢型谷氨酸受体5（mGluR5）为靶标进行免疫荧光标记，荧光信号呈红色；以α-突触核蛋白（alpha synuclein）为靶标进行免疫荧光标记，荧光信号呈绿色；并使用DAPI（4',6-二脒基-2-苯基吲哚）进行复染，荧光信号呈蓝色以显示细胞核。