Ventrointermediate thalamic stimulation improves motor learning in humans: data sets

Ventrointermediate thalamic stimulation (VIM-DBS) modulates oscillatory activity in a cortical network including primary motor cortex, premotor cortex, and parietal cortex. Here we show that, beyond the beneficial effects of VIM-DBS on motor execution, this form of invasive stimulation facilitates production of sequential finger movements that follow a repeated sequence. These results highlight the role of thalamo–cortical activity in motor learning.Behavioral data (mean normalized learning score), for each participant over time, depending on condition (DBS-ON, DBS-OFF). Power Block 4, Power contrast over time, and regression.All datasets contain grand-average event-related spectral perturbation data for DBS-ON and DBS-OFF, the grand-average difference (DBS-OFF minus DBS-ON), and cluster-based permutation test results. Tests and datasets for all trials Block 4, Block 4 learned, Block 4 random, contrast Block 4 minus Block 1 learned, contrast Block 4 minus Block 1 random.

丘脑腹中间核脑深部电刺激（Ventrointermediate thalamic stimulation, VIM-DBS）可调控包含初级运动皮层、运动前皮层与顶叶皮层的皮层网络内的振荡活动。本研究表明，除该刺激对运动执行的有益作用外，这种侵入式脑刺激还可促进遵循重复序列的连续手指运动的生成。上述结果凸显了丘脑-皮层活动在运动学习中的关键作用。
行为数据（归一化学习得分均值）：按实验条件（脑深部电刺激开启、脑深部电刺激关闭）分组，展示每位参与者随时间变化的学习表现。
数据集涵盖第4组块功率数据、随时间变化的功率对比数据以及回归分析数据。所有数据集均包含脑深部电刺激开启与关闭条件下的总平均事件相关频谱扰动数据、总平均差值（脑深部电刺激关闭减开启）结果，以及基于簇的置换检验结果。本研究的实验与测试数据集覆盖所有试次类型，具体包括：第4组块试次、第4组块习得序列试次、第4组块随机序列试次，以及第4组块与第1组块习得序列试次的对比数据、第4组块与第1组块随机序列试次的对比数据。