Novel cryo-racks for different applications in biobanking.

While the freezing of cell suspensions is easy to handle since the discovery of cryoprotective agents, the cryopreservation of living tissue is still problematic today. Sophisticated controlled rate freezers for biological samples provide a high cooling performance as well as outstanding freezing rates which should allow reproducible tissue freezing. However, the required temperature homogeneity for multiple sample positions cannot be achieved even with the freezing equipment for biological samples currently available. For this reason, we have developed a range of thermal management units. For instance, our novel Multiwell RACK can cryopreserve up to 96 tissue models by use of the microwell format.

尽管自冷冻保护剂（cryoprotective agents）问世以来，细胞悬液的冷冻操作已简便易行，但活体组织的冷冻保存至今仍是亟待解决的技术难题。针对生物样本的高端程序降温冷冻仪（controlled rate freezers）具备优异的制冷性能与出色的降温速率，理论上可实现可重复的组织冷冻流程。然而，即便使用当前已有的生物样本冷冻设备，仍无法满足多样本放置位点所需的温度均匀性（temperature homogeneity）要求。为此，我们研发了一系列热管理单元。例如，我们全新推出的Multiwell RACK可借助微孔板格式，实现最多96个组织模型的冷冻保存。