Beta-ketoacyl-acyl carrier protein synthase III-2 (FabH2)(C113A) from Vibrio cholerae

NIAID Data Ecosystem2026-05-01 收录

脂肪酸合成

抗菌靶点研究

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Beta-ketoacyl-acyl carrier protein synthase III-2 (FabH2)(C113A) from Vibrio cholerae

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2023-09-27

Crystal structure of BT-CD domains of human acetyl-CoA carboxylase

酶晶体结构

脂肪酸合成

Crystal structure of BT-CD domains of human acetyl-CoA carboxylase Descriptor: BT-CD domains of human acetyl-CoA carboxylase, CADMIUM ION Authors: Stuttfeld, E, Hunkeler, M, Hagmann, A, Imseng, S, Mai

Protein Data Bank Japan2024-11-13 更新90

Crystal structure of FabG from Cupriavidus taiwanensis

蛋白质晶体学

脂肪酸合成

Crystal structure of FabG from Cupriavidus taiwanensis

NIAID Data Ecosystem30

2.0 Angstrom Crystal Structure of an Acyl Carrier Protein S-malonyltransferase from Salmonella typhimurium.

蛋白质晶体学

脂肪酸合成

2.0 Angstrom Crystal Structure of an Acyl Carrier Protein S-malonyltransferase from Salmonella typhimurium.

NIAID Data Ecosystem10

The Tat system and its dependent cell division proteins are critical for virulence of extra-intestinal pathogenic Escherichia coli

细菌致病机制

抗菌靶点研究

The twin-arginine translocation (Tat) system is involved in a variety of important bacterial physiological processes. Conserved among bacteria and crucial for virulence, the Tat system is deemed as a

NIAID Data Ecosystem40

This study shows that S. aureus is more versatile than recently concluded. First, mutants selected on the FabI inhibitor triclosan are about 100-fold more frequent when fatty acids are available. A novel FASII bypass target is identified as FabD, a malonyl CoA-acyl carrier protein transacylase.

细菌耐药性机制

脂肪酸合成

Antimicrobials targeting the fatty acid synthesis pathway (FASII) may be bypassed by numerous pathogens that incorporate host fatty acids. This activity would greatly restrict use of anti-FASII drugs.

NIAID Data Ecosystem10

Beta-ketoacyl-acyl carrier protein synthase III-2 (FabH2)(C113A) from Vibrio cholerae

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