Structure of the thermostabilized EAAT1 cryst mutant in complex with the competititve inhibitor TFB-TBOA and the allosteric inhibitor UCPH101
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Structure of the thermostabilized EAAT1 cryst mutant in complex with the competititve inhibitor TFB-TBOA and the allosteric inhibitor UCPH101 Descriptor: (2~{S},3~{S})-2-azanyl-3-[[3-[[4-(trifluoromethyl)phenyl]carbonylamino]phenyl]methoxy]butanedioic acid, 2-Amino-5,6,7,8-tetrahydro-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-4H-chromene-3-carbonitrile, Excitatory amino acid transporter 1,Neutral amino acid transporter B(0),Excitatory amino acid transporter 1 Authors: Canul-Tec, J, Assal, R, Legrand, P, Reyes, N. Deposit date: 2016-12-01 Release date: 2017-04-19 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (3.71 Å) Cite: Structure and allosteric inhibition of excitatory amino acid transporter 1. Nature, 544, 2017
创建时间:
2016-12-01



