Characteristics of variable Deoxyribonuclease I hypersensitive sites.

The table shows features of the most variable Deoxyribonuclease I hypersensitive sites (identified at FDR threshold of 1%, equivalent to an adjusted P-value of 0.008), compared to non variable peaks. The features shown are the percentage of sites containing sequence variants (Variants), the percentage of sites showing sequence conservation (Conservation), the percentage of sites with the signature of an enhancer (Enhancer) and those with the signature of a promoter (Promoter). The P-value is that obtained from estimating peak differences between strains (modeled as a negative binomial distribution). Results are shown for comparisons between the most variable peaks and three sets of non-variable peaks, defined at different stringencies (P-values>0.008, 0.5 and 0.97). The significance of the comparison is shown as the negative logarithm (base 10) of the P-value of a Fisher exact test.