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EGFR(T790M/V948R) in complex with Lazertinib (YH25448)

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Protein Data Bank Japan2024-10-16 更新2026-04-19 收录
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EGFR(T790M/V948R) in complex with Lazertinib (YH25448) Descriptor: Epidermal growth factor receptor, N-[5-{[(4P)-4-{4-[(dimethylamino)methyl]-3-phenyl-1H-pyrazol-1-yl}pyrimidin-2-yl]amino}-4-methoxy-2-(morpholin-4-yl)phenyl]propanamide Authors: Pham, C.D, Heppner, D.E. Deposit date: 2022-04-02 Release date: 2022-11-23 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Structural Basis for Inhibition of Mutant EGFR with Lazertinib (YH25448). Acs Med.Chem.Lett., 13, 2022

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2022-04-02
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