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Durable Response of Enzalutamide-resistant Prostate Cancer to Supraphysiological Testosterone Is Associated with a Multifaceted Growth Suppression and Impaired DNA Damage Response Transcriptomic Program in Patient-derived Xenografts

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干细胞与再生医学数据中心2022-02-20 更新2024-03-06 收录
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http://data.iscr.ac.cn/Article?id=920df3c37ec477420d25d726c0e1e1b6
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The study aims to determine SPT effect on the CRPC growth and molecular alterations using LuCaP PDX CRPC models.

本研究旨在借助LuCaP患者来源异种移植(Patient-Derived Xenograft,PDX)去势抵抗性前列腺癌(Castration-Resistant Prostate Cancer,CRPC)模型,明确SPT对CRPC生长及分子改变的影响。
提供机构:
Fred Hutchinson Cancer Research Center
创建时间:
2022-02-20
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