Raw Data from: Modification of Natural Clays with Magnetite to Provide their Boosted Antimicrobial Properties and Chemopreventive Activity against Melanoma

The aim of the study was to synthesize and characterize Fe3O4-loaded clays, which can be potentially used as a component of dressing materials designed for the management of chronic and infected wounds. Moreover, it was assumed that selective toxicity of Fe3O4 nanoparticles towards cancer cells may provide an additional benefit of magnetite–clay complexes in the treatment of post-oncological skin wounds, where the complex can significantly reduce viability of remaining tumor cells after skin cancer resection, providing a chemopreventive effect. The magnetite-clay complexes were synthesized by the chemical co-precipitation method and characterized using XRD, TEM, STEM-EDS, SEM, and SQUID magnetometer. Antimicrobial properties were determined by evaluation of MIC values. Cytotoxicity of the complexes towards melanoma cells and normal human skin fibroblasts was assessed by MTT assay.

Microsoft Excel file (.xlsx) entitled ‘MIC evaluation’ contains the raw results of MIC estimation. Abbreviation of the samples: M – montmorillonite, MMT – Fe3O4- montmorillonite, B – bentonite, MB – Fe3O4-bentonite, K – kaolinite, MK – Fe3O4- kaolinite, G – glauconite, MG – Fe3O4-glauconite

Folder entitled ‘Cytotoxicity test’ contains 2 Microsoft Excel files (.xlsx) presenting raw MTT results either for BJ fibroblasts or A375 melanoma cells (file name indicates the type of cells used).

Folder entitled ‘SEM’ contains raw SEM images (.TIF) of the samples.

Folder entitled ‘SQUID Magnetometer’ contains original data (.dat files) obtained with the Magnetometer (file name indicates the type of sample) as well as raw data for all samples exported to Microsoft Excel file (.xlsx).

Folder entitled ‘XRD’ contains original data from XRD (.xrdml files). File name indicates the type of sample.

Folder entitled ‘TEM’ contains raw TEM micrographs of magnetite nanoparticles (.TIF) and Microsoft Excel file (.xlsx) with raw data for the measurement of particle length distribution.

Folder entitled ‘STEM-EDS’ contains raw micrographs of STEM-EDS mapping (.TIF)