Exploring the molecular mechanism of Bushen Huoxue Fang on premature ovarian failure based on transcriptomics and systems biology. Exploring the molecular mechanism of Bushen Huoxue Fang on premature ovarian failure based on transcriptomics and systems biology

Objective: To Explore the mechanism of autophagy in mice with immune premature ovarian failure (POF) and the effect of Bushen Huoxue Fang (BSHXF) Method: POF mice were treated with BSHXF, and estradiol valerate. Then, the ovaries were used for transcriptome sequencing. Overall design: Comparative gene expression profiling analysis of RNA-seq data for POF mice and BSHXF treated mice