Scalable Total Syntheses of (±)-Catellatolactams A and B
收藏Figshare2023-02-07 更新2026-04-28 收录
下载链接：
https://figshare.com/articles/dataset/Scalable_Total_Syntheses_of_-Catellatolactams_A_and_B/22040592
下载链接
链接失效反馈官方服务：
资源简介：
The first total syntheses of (±)-catellatolactams A and B, two novel ansamacrolactams, are described in 5 and 8 steps, respectively. The strategy relies on an amidation reaction to couple the acylated Meldrum’s acid and an aryl amine, a regioselective C–H insertion to construct the γ-lactam moiety, and an RCM reaction to forge the macrocycles with E-olefin. This concise and scalable synthesis provided over 200 mg of the target molecules.
创建时间：
2023-02-07
