Crystal structure of HCV NS3/4A WT protease in complex with AJ-21 (MK-5172 linear analogue)
收藏Protein Data Bank Japan2023-10-04 更新2026-03-21 收录
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Crystal structure of HCV NS3/4A WT protease in complex with AJ-21 (MK-5172 linear analogue) Descriptor: 3-methyl-N-[(pentyloxy)carbonyl]-L-valyl-(4R)-4-[(3-chloro-7-methoxyquinoxalin-2-yl)oxy]-N-[(1R,2S)-2-ethenyl-1-{[(1-methylcyclopropyl)sulfonyl]carbamoyl}cyclopropyl]-L-prolinamide, GLYCEROL, NS3 protease, ... Authors: Matthew, A.N, Schiffer, C.A. Deposit date: 2018-03-29 Release date: 2018-08-08 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.798 Å) Cite: Quinoxaline-Based Linear HCV NS3/4A Protease Inhibitors Exhibit Potent Activity against Drug Resistant Variants. ACS Med Chem Lett, 9, 2018
创建时间:
2018-03-29



