Progesterone activation of β1-containing BK channels involves two novel binding sites

Our study provides a new model for progesterone to interact with BK channel beta1 subunits and eventually activate these channels leading to cerebrovascular dilation.本研究构建了孕酮（progesterone）与大电导钙激活钾通道（BK channel）β1亚基相互作用，最终激活该类通道并介导脑血管舒张的全新模型。