Subclinical mastitis lipidomics

We demonstrated that sub-clinical intramammary infection (IMI) with non-aureus staphylococci (NAS) induces changes in the milk lipidome. By applying an untargeted approach, we observed that the abundance of 597 lipids is modified over ten fold due to NAS IMI. Our results contribute to the understanding of inflammatory processes in the bovine udder, highlighting potential novel biomarkers for improving mastitis diagnosis

本研究证实，非金黄色葡萄球菌（non-aureus staphylococci, NAS）引发的亚临床乳腺内感染（sub-clinical intramammary infection, IMI）可改变牛奶脂质组（milk lipidome）。通过采用无靶标分析方法，我们观测到受NAS引发的IMI影响后，共有597种脂质的丰度发生了十倍以上的变化。本研究结果有助于深化对牛乳腺炎症过程的认知，并为优化乳腺炎诊断提供了潜在的新型生物标志物。